导师类型

硕士生导师

办公地点

6教308

职称/职务

副教授

电子邮箱

xinghong.zhao@sicau.edu.cn

研究方向

新型肽类抗菌剂（基因组发掘与生物合成）、仿生纳米载药系统、细菌耐药性防控

学术、技术组织任职/头衔

四川省特聘专家、入选四川省“天府峨眉计划”、荷兰皇家微生物学学会会员、美国微生物学会会员、Frontiers in Microbiology(IF=6.604, Top)客座编辑（Guest Editor）。

教育背景及工作经历

2023/03至今金沙威尼斯欢乐娱人城副教授

2021/08-2023/02 金沙威尼斯欢乐娱人城特聘副教授

2020/06–2021/08荷兰格罗宁根大学微生物与生化药学博士后

2017/08–2020/06荷兰格罗宁根大学微生物与生化药学博士

教学课程

生物技术制药、仪器分析（药）、药学专业英语

人才培养情况

指导在读硕士生5名、本科生14名。

科研项目

（近五年）

1、天府英才工程专项，2023.04-2026.03，在研，主持

2、四川省国际科技创新合作项目，202201-202312，结题，主持

3、金沙威尼斯欢乐娱人城引进人才科研启动项目，202108-202607，在研，主持

4、四川省博士后科研项目特别资助，202307-202507，在研，主持

主要论著、

代表性论文

现已发表SCI收录论文30余篇，累计被引1200余次，H指数20。研究成果发表在包括NatureCommunications、Cell Chemical biology、Journal of Controlled Release、Advanced Healthcare Materials、International Journal of Biological Macromolecules和Antimicrobialagents and chemotherapy等权威期刊。

[1]Xinghong Zhao^#,*, Xinyi Zhong^#, Shinong Yang^#, Jiarong Deng, Kai Deng, Zhengqun Huang, Yuanfeng Li, Zhongqiong Yin*, Yong Liu*, Jakob H. Viel, and Hongping Wan*. "Guiding antibiotics towards their target using bacteriophage proteins."NatureCommunications,2024, 15: 5287.（IF = 16.6，物理第一作者兼共同通讯作者）

[2]Xinghong Zhao, Zhibo Li, and Oscar P. Kuipers*. "Mimicry of a Non-ribosomally Produced Antimicrobial, Brevicidine, by Ribosomal Synthesis and Post-translational Modification."Cell Chemical Biology,2020, 27(10): 1262-1271.（IF = 9.039，第一作者）

[3] Kai Deng^#, Zhengqun Huang^#, Bo Jing, Lin Zhu, Yumei Feng, Qin Jiang, Zhiwen Xu, Hongping Wan*, andXinghong Zhao*. "Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization."International Journal of Biological Macromolecules,2024, 133008.（IF = 8.2，最后通讯作者）

[4] Yumeng Wang^#,Xinghong Zhao^#, Xingjian Zhou^#, Juqin Dai, Xiaowen Hu, Yinzi Piao, Guangyue Zu, Jian Xiao*, Keqing Shi*, Yong Liu*, Yuanfeng Li*, and Linqi Shi. "A supramolecular hydrogel dressing with antibacterial, immunoregulation, and pro-regeneration ability for biofilm-associated wound healing."Journal of Controlled Release,2024, 368:740-755.（IF = 10.8，共同第一作者）

[5] Hongping Wan^#,*, Kai Deng^#, Zhengqun Huang^#, Yunhan Yang, Bo Jing, Yumei Feng, Yuanfeng Li, Yong Liu, Mingqin Liu, andXinghong Zhao*. "Pathogen-mimicking Nanoparticles Based on Rigid Nanomaterials as an Efficient Subunit Vaccine Delivery System for Intranasal Iimmunization."Advanced Healthcare Materials,2024, 2401120.（IF = 10，最后通讯作者）

[6]Xinghong Zhao^#,*, Xinyi Zhong^#, Shinong Yang^#, Kai Deng, Lu Liu, Xu Song, Yuanfeng Zou, Lixia Li, Xun Zhou, Renyong Jia, Juchun Lin, Huaqiao Tang, Gang Ye, Jianqing Yang, Shan Zhao, Yifei Lang, Hongping Wan*, Zhongqiong Yin*, and Oscar P. Kuipers. "Elucidating the Mechanism of Action of the Gram-Negative-Pathogen-Selective Cyclic Antimicrobial Lipopeptide Brevicidine."Antimicrobial Agents and Chemotherapy,2023:e00010-23.（IF = 5.938，物理第一作者兼共同通讯作者）

[7]Xinghong Zhao, Zhongqiong Yin, Eefjan Breukink, Gert N. Moll, and Oscar P. Kuipers*. "An engineered double lipid II binding motifs-containing lantibiotic displays potent and selective antimicrobial activity against Enterococcus faecium."Antimicrobial Agents and Chemotherapy,2020, 64(6): e02050-19.（IF = 5.938，第一作者）

[8] Roderick Corstiaan Abraham Versloot, Patricia Arias-Orozco, Matthijs Jonathan Tadema, Florian Leonardus Rudolfus Lucas,Xinghong Zhao, Siewert J. Marrink, Oscar Paul Kuipers, and Giovanni Maglia*. "Seeing the Invisibles: Detection of Peptide Enantiomers, Diastereomers, and Isobaric Ring Formation in Lanthipeptides Using Nanopores."Journal of the American Chemical Society,2023, 145(33):18355-18365.（IF = 15）

[9]Xinghong Zhao, and Oscar P. Kuipers*. "Nisin-and ripcin-derived hybrid lanthipeptides display selective antimicrobial activity against Staphylococcus aureus."ACS Synthetic Biology,2021, 10(7): 1703-1714.（IF = 5.249，第一作者）

[10]Xinghong Zhao, and Oscar P. Kuipers*. "Synthesis of silver-nisin nanoparticles with low cytotoxicity as antimicrobials against biofilm-forming pathogens"Colloids and Surfaces B: Biointerfaces,2021, 206: 111965.（IF = 5.999，第一作者）